Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tnnt2  troponin T2, cardiac   (Synonyms: cardiac TnT, cTnT, Tnt)
Results	Reference
1*	J:293794 Durbin MD, O'Kane J, Lorentz S, Firulli AB, Ware SM, SHROOM3 is downstream of the planar cell polarity pathway and loss-of-function results in congenital heart defects. Dev Biol. 2020 Aug 15;464(2):124-136
1	J:239361 Guimaraes-Camboa N, Stowe J, Aneas I, Sakabe N, Cattaneo P, Henderson L, Kilberg MS, Johnson RS, Chen J, McCulloch AD, Nobrega MA, Evans SM, Zambon AC, HIF1alpha Represses Cell Stress Pathways to Allow Proliferation of Hypoxic Fetal Cardiomyocytes. Dev Cell. 2015 Jun 08;33(5):507-21
1	J:239830 Hirai M, Arita Y, McGlade CJ, Lee KF, Chen J, Evans SM, Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation. J Clin Invest. 2017 Feb 01;127(2):569-582
1	J:245319 Jain R, Li D, Gupta M, Manderfield LJ, Ifkovits JL, Wang Q, Liu F, Liu Y, Poleshko A, Padmanabhan A, Raum JC, Li L, Morrisey EE, Lu MM, Won KJ, Epstein JA, HEART DEVELOPMENT. Integration of Bmp and Wnt signaling by Hopx specifies commitment of cardiomyoblasts. Science. 2015 Jun 26;348(6242):aaa6071
1	J:183083 Katz TC, Singh MK, Degenhardt K, Rivera-Feliciano J, Johnson RL, Epstein JA, Tabin CJ, Distinct compartments of the proepicardial organ give rise to coronary vascular endothelial cells. Dev Cell. 2012 Mar 13;22(3):639-50
1	J:219384 Lescroart F, Chabab S, Lin X, Rulands S, Paulissen C, Rodolosse A, Auer H, Achouri Y, Dubois C, Bondue A, Simons BD, Blanpain C, Early lineage restriction in temporally distinct populations of Mesp1 progenitors during mammalian heart development. Nat Cell Biol. 2014 Sep;16(9):829-40
1*	J:238546 Li J, Liu Y, Jin Y, Wang R, Wang J, Lu S, VanBuren V, Dostal DE, Zhang SL, Peng X, Essential role of Cdc42 in cardiomyocyte proliferation and cell-cell adhesion during heart development. Dev Biol. 2017 Jan 15;421(2):271-283
1	J:332317 Lin X, Swedlund B, Ton MN, Ghazanfar S, Guibentif C, Paulissen C, Baudelet E, Plaindoux E, Achouri Y, Calonne E, Dubois C, Mansfield W, Zaffran S, Marioni JC, Fuks F, Gottgens B, Lescroart F, Blanpain C, Mesp1 controls the chromatin and enhancer landscapes essential for spatiotemporal patterning of early cardiovascular progenitors. Nat Cell Biol. 2022 Jul;24(7):1114-1128
1	J:340446 Lotto J, Cullum R, Drissler S, Arostegui M, Garside VC, Fuglerud BM, Clement-Ranney M, Thakur A, Underhill TM, Hoodless PA, Cell diversity and plasticity during atrioventricular heart valve EMTs. Nat Commun. 2023 Sep 9;14(1):5567
1	J:238888 Luo W, Zhao X, Jin H, Tao L, Zhu J, Wang H, Hemmings BA, Yang Z, Akt1 signaling coordinates BMP signaling and beta-catenin activity to regulate second heart field progenitor development. Development. 2015 Feb 15;142(4):732-42
1	J:237617 Menendez-Montes I, Escobar B, Palacios B, Gomez MJ, Izquierdo-Garcia JL, Flores L, Jimenez-Borreguero LJ, Aragones J, Ruiz-Cabello J, Torres M, Martin-Puig S, Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch Essential for Cardiac Maturation. Dev Cell. 2016 Dec 19;39(6):724-739
1*	J:207639 Nelson DO, Jin DX, Downs KM, Kamp TJ, Lyons GE, Irx4 identifies a chamber-specific cell population that contributes to ventricular myocardium development. Dev Dyn. 2014 Mar;243(3):381-92
1	J:309998 Nie X, Ricupero CL, Jiao K, Yang P, Mao JJ, mTOR deletion in neural crest cells disrupts cardiac outflow tract remodeling and causes a spectrum of cardiac defects through the mTORC1 pathway. Dev Biol. 2021 Sep;477:241-250
1	J:134635 Peng X, Wu X, Druso JE, Wei H, Park AY, Kraus MS, Alcaraz A, Chen J, Chien S, Cerione RA, Guan JL, Cardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout mice. Proc Natl Acad Sci U S A. 2008 May 6;105(18):6638-43
1	J:199136 Rog-Zielinska EA, Thomson A, Kenyon CJ, Brownstein DG, Moran CM, Szumska D, Michailidou Z, Richardson J, Owen E, Watt A, Morrison H, Forrester LM, Bhattacharya S, Holmes MC, Chapman KE, Glucocorticoid receptor is required for foetal heart maturation. Hum Mol Genet. 2013 Aug 15;22(16):3269-82
1*	J:244087 Stopp S, Grundl M, Fackler M, Malkmus J, Leone M, Naumann R, Frantz S, Wolf E, von Eyss B, Engel FB, Gaubatz S, Deletion of Gas2l3 in mice leads to specific defects in cardiomyocyte cytokinesis during development. Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):8029-8034
1	J:254120 Villa Del Campo C, Lioux G, Carmona R, Sierra R, Munoz-Chapuli R, Claveria C, Torres M, Myc overexpression enhances of epicardial contribution to the developing heart and promotes extensive expansion of the cardiomyocyte population. Sci Rep. 2016 Oct 18;6:35366
1*	J:306325 Wang Y, Jiang T, Xu J, Gu Y, Zhou Y, Lin Y, Wu Y, Li W, Wang C, Shen B, Mo X, Wang X, Zhou B, Ding C, Hu Z, Mutations in RNA Methyltransferase Gene NSUN5 Confer High Risk of Outflow Tract Malformation. Front Cell Dev Biol. 2021;9:623394
1	J:226315 Ye W, Wang J, Song Y, Yu D, Sun C, Liu C, Chen F, Zhang Y, Wang F, Harvey RP, Schrader L, Martin JF, Chen Y, A common Shox2-Nkx2-5 antagonistic mechanism primes the pacemaker cell fate in the pulmonary vein myocardium and sinoatrial node. Development. 2015 Jul 15;142(14):2521-32
1	J:312367 Yuko AE, Carvalho Rigaud VO, Kurian J, Lee JH, Kasatkin N, Behanan M, Wang T, Luchesse AM, Mohsin S, Koch WJ, Wang H, Khan M, LIN28a induced metabolic and redox regulation promotes cardiac cell survival in the heart after ischemic injury. Redox Biol. 2021 Oct 8;47:102162
1	J:321836 Zhao K, Huang X, Zhao W, Lu B, Yang Z, LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development. Development. 2022 Mar 15;149(6):dev200458
1	J:261328 Zou J, Ma W, Li J, Littlejohn R, Zhou H, Kim IM, Fulton DJR, Chen W, Weintraub NL, Zhou J, Su H, Neddylation mediates ventricular chamber maturation through repression of Hippo signaling. Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4101-E4110
1*	J:333036 Zou J, Wang W, Lu Y, Ayala J, Dong K, Zhou H, Wang J, Chen W, Weintraub NL, Zhou J, Li J, Su H, Neddylation is required for perinatal cardiac development through stimulation of metabolic maturation. Cell Rep. 2023 Jan 31;42(1):112018